Search results for "Disorders of the Nervous System"

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Early Social Isolation Stress and Perinatal NMDA Receptor Antagonist Treatment Induce Changes in the Structure and Neurochemistry of Inhibitory Neuro…

2017

AbstractThe exposure to aversive experiences during early life influences brain development and leads to altered behavior. Moreover, the combination of these experiences with subtle alterations in neurodevelopment may contribute to the emergence of psychiatric disorders, such as schizophrenia. Recent hypotheses suggest that imbalances between excitatory and inhibitory (E/I) neurotransmission, especially in the prefrontal cortex and the amygdala, may underlie their etiopathology. In order to understand better the neurobiological bases of these alterations, we studied the impact of altered neurodevelopment and chronic early-life stress on these two brain regions. Transgenic mice displaying fl…

Interneuron3PSA-NCAMsocial isolationSynaptophysinPrefrontal CortexMice TransgenicinterneuronNeurotransmissionInhibitory postsynaptic potentialReceptors N-Methyl-D-AspartateSynaptic TransmissionAmygdalastressNeuroplasticitymedicineAnimalsNeurochemistryPrefrontal cortexNeuronsNeuronal PlasticityGeneral Neuroscience3.1General MedicineNew ResearchAmygdalaschizophreniamedicine.anatomical_structureNMDA receptorDisorders of the Nervous SystemDizocilpine MaleatePsychologyNeuroscienceeneuro

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PEPhysical Sciences and Engineering
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LSLife Sciences
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- LS5Neuroscience and Disorders of the Nervous System
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SHSocial Sciences and Humanities
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